Complementarity Determining Regions

Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).

Also Known As:

Complementarity Determining Region; Complementarity Determining Region 1; Complementarity Determining Region 2; Complementarity Determining Region 3; Complementarity Determining Region I; Complementarity Determining Region II; Complementarity Determining Region III; Complementarity-Determining Region; Complementarity-Determining Region 3; Hypervariable Region, Immunoglobulin; Hypervariable Regions, Immunoglobulin; Third Complementarity-Determining Region; Complementarity-Determining Region 3s; Complementarity-Determining Region, Third; Complementarity-Determining Regions; Complementarity-Determining Regions, Third; Immunoglobulin Hypervariable Region; Immunoglobulin Hypervariable Regions; Region, Complementarity Determining; Region, Immunoglobulin Hypervariable; Regions, Complementarity Determining; Regions, Complementarity-Determining; Regions, Immunoglobulin Hypervariable; Third Complementarity Determining Region; Third Complementarity-Determining Regions

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Blood Proteins: 12679
    - Serum Globulins: 555
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fab Fragments: 766
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
    - Immunoproteins: 43
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fab Fragments: 766
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
  - Membrane Proteins: 10262
    - Cell Surface Receptors: 2156
      - Immunologic Receptors: 10
        Antigen Receptors: 758
        T-Cell Antigen Receptors: 7477
        Complementarity Determining Regions: 337
  - Globulins: 3119
    - Serum Globulins: 555
      - Immunoglobulins: 30911
        Immunoglobulin Fragments: 979
        Immunoglobulin Fab Fragments: 766
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
- Peptides: 84029
  - Peptide Fragments: 379
    - Immunoglobulin Fragments: 979
      - Immunoglobulin Fab Fragments: 766
        Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337
Chemical Phenomena
- Biochemical Phenomena
  - Molecular Structure
    - Amino Acid Sequence
      - Immunoglobulin Variable Region: 208
        Complementarity Determining Regions: 337

Anna B M Black Selected Research

Anna B M Black Research Topics

Disease

Drug/Important Bio-Agent (IBA)